Hiroyuki Kouji Selected Research

ICG 001

2/2022	Involvement of activator protein-1 family members in β-catenin and p300 association on the genome of PANC-1 cells.
9/2020	Anti-tumor Activity of the Small Molecule Inhibitor PRI-724 Against β-Catenin-activated Hepatocellular Carcinoma.
12/2019	β-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis.
12/2019	Selective Inhibition of β-Catenin/Co-Activator Cyclic AMP Response Element-Binding Protein-Dependent Signaling Prevents the Emergence of Hapten-Induced Atopic Dermatitis-Like Dermatitis.
1/2019	The novel inhibitor PRI-724 for Wnt/β-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice.

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Hiroyuki Kouji Research Topics

Disease

5	Neoplasms (Cancer) 04/2022 - 12/2019
2	Hypoxia (Hypoxemia) 01/2021 - 01/2021
2	Fibrosis (Cirrhosis) 12/2019 - 12/2019
2	Pain (Aches) 10/2017 - 07/2016
1	Pancreatic Neoplasms (Pancreatic Cancer) 02/2022
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2021
1	Stomach Neoplasms (Stomach Cancer) 01/2021
1	Colonic Neoplasms (Colon Cancer) 01/2021
1	Polyps 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 09/2020
1	Skin Diseases (Skin Disease) 12/2019
1	Cysts 12/2019
1	Endometriosis 12/2019
1	Asthma (Bronchial Asthma) 12/2019
1	Dermatitis 12/2019
1	Atopic Dermatitis (Atopic Eczema) 12/2019
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2019
1	Autistic Disorder (Autism) 01/2019
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2019
1	Neuralgia (Stump Neuralgia) 10/2017
1	Weight Loss (Weight Reduction) 07/2016
1	Inflammation (Inflammations) 04/2007

Drug/Important Bio-Agent (IBA)

6	CateninsIBA 02/2022 - 01/2019
5	ICG 001IBA 02/2022 - 01/2019
2	RNA (Ribonucleic Acid)IBA 02/2022 - 01/2021
2	CREB-Binding ProteinIBA 01/2021 - 12/2019
1	Proteins (Proteins, Gene)FDA Link 04/2022
1	Transcription Factors (Transcription Factor)IBA 04/2022
1	Messenger RNA (mRNA)IBA 04/2022
1	ChromatinIBA 02/2022
1	Peptides (Polypeptides)IBA 08/2021
1	Antiviral Agents (Antivirals)IBA 08/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	Alkenes (Olefins)IBA 01/2021
1	Antineoplastic Agents (Antineoplastics)IBA 01/2021
1	Chemokine CCL17IBA 12/2019
1	Thymic Stromal LymphopoietinIBA 12/2019
1	HaptensIBA 12/2019
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 12/2019
1	Valproic Acid (Depakote)FDA LinkGeneric 01/2019
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2019
1	Morphine (MS Contin)FDA LinkGeneric 10/2017
1	agomelatine (S20098)IBA 07/2016
1	RE1-silencing transcription factorIBA 07/2016
1	Antidepressive Agents (Antidepressants)IBA 07/2016
1	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 04/2007
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 04/2007
1	LigandsIBA 04/2007

Therapy/Procedure

2	Therapeutics 12/2019 - 01/2019
1	Aftercare (After-Treatment) 12/2019
1	Analgesia 10/2017